Although there are many benefits of eating persimmon, there are a few points that we must beware of: 

1. Persimmons Should Not Be Eaten On An Empty Stomach.    Contains more tannin and pectin, in an empty stomach under the effect of gastric acid, lumps of various sizes will be formed, if these lumps can not reach the pyloric intestine, they will remain in the stomach to form gastric persimmon stone.   The stone originally is as small as apricots and persimmon seeds, but will tend to get larger. If  not naturally expelled from the stomach, it will cause diospyrobezoar the digestive tract obstruction, resulting in upper abdominal pain, vomiting, and even vomiting blood and other symptoms. During surgery, persimmon stone as big as a fist was found in the stomach. If there's food in the stomach then the persimmon stone formation in the stomach can be avoided .

2. Persimmon Skin Should Not Be Eaten     Some people feel that eating persimmon fruit together with the skin taste better than just eating the flesh by itself.  Scientifically this is not advisable because the vast majority of persimmon tannin is concentrated in the skin. If eaten together with its skin the formation of gastric persimmon stone is easier, especially when the astringent process is incomplete, as its skin contains more tannic acid. 

3... Do not eat pesimmon together with  high-protein crabs, fish, shrimp and other foods     In Chinese medicine, crab and persimmon are considered "cold foods", therefore they cannot be eaten together. From the perspective of modern medicine, crab, fish and shrimp contains high level of protein and thus under the effect of the tannic acid, it is easy to solidify into blocks, namely, stomach persimmon stone.

4. Diabetics Should Not Eat Pesimmon     Persimmon has 10.8%  sugars content, and most are simple pairs of sugar and simple sugars (sucrose, fructose, glucose is such), which can easily be absorbed by our body after eating which may result in hyperglycemia. For diabetic people, especially those with poor glycemic control, it is even more harmful. 

5. Enough is enough     The tannic acid in persimmon together with dietary calcium, zinc, magnesium, iron and other minerals form compounds that cannot be absorbed by the body so that these nutrients can not be used and therefore eating persimmons can easily lead to a lack of these minerals. And because there is more sugar in persimmon, eating the same amount of persimmon compared to apples or pears will make one feel full faster hence will affect one's appetite, and reduce the intake of meals. Generally, with an empty stomach, it is advisable that not more than 200 grams of persimmon should be taken.